From smoky mezcal cocktails to handcrafted plates that honor tradition while pushing boundaries — Mezcal Comida & Cantina is where West Ave comes alive.
Craft Cocktails
Mezcal & tequila bar
Live Music
Weekend performances
Private Events
Celebrations & gatherings
Fresh Ingredients
Locally sourced daily
Every dish tells a story — from the smoke of our mezcal-fired cocktails to the slow-crafted traditions behind every plate.
Smoky reposado mezcal, agave nectar, fresh lime, and a hint of chipotle. Served up with a charred orange twist.
Slow-roasted pork marinated in achiote and guajillo, grilled pineapple, diced onion, and fresh cilantro on corn tortillas.
Corn tortillas filled with shredded chicken, smothered in tangy tomatillo sauce, topped with crema and queso fresco.
Hand-mashed avocados with Roma tomatoes, white onion, cilantro, jalapeño, and a squeeze of fresh lime. Prepared right at your table.
Our signature mole made from over 20 ingredients — chocolate, chiles, spices — braised slowly and poured over tender chicken.
Crispy golden churros dusted with cinnamon sugar, served with a rich dark chocolate sauce infused with cayenne.
Mezcal Comida & Cantina was born from a simple conviction: San Antonio deserves a restaurant that honors the depth of Mexican cuisine while creating something entirely its own.
Our kitchen draws from generations of regional recipes — the slow braises of Oaxaca, the street-corner sizzle of Mexico City, the coastal flavors of the Pacific — and reimagines them with locally sourced ingredients and a modern sensibility.
Every mezcal on our shelf is sourced directly from small producers. Every dish is prepared with intention. Every guest is treated like family.
From the bar to the kitchen to your table — every corner of Mezcal is designed to feel like home.
Whether it's a birthday, a corporate gathering, or an anniversary dinner — Mezcal Comida & Cantina offers flexible spaces tailored to your occasion.
Walk in or call ahead — we always save a seat for someone new. Your table at San Antonio's favorite cantina is waiting.
We're on West Ave in the heart of San Antonio. Pull up a chair — we'd love to host you.
12656 West Ave
San Antonio, TX 78216-1800
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